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http://purl.uniprot.org/citations/14690600http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14690600http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14690600http://www.w3.org/2000/01/rdf-schema#comment"Human cleavage factor I(m) (CFI(m)) is a heterodimeric RNA binding protein complex that functions at an early step in the assembly of the pre-mRNA 3' processing complex. In this report we show that CFI(m) can stimulate both cleavage and poly(A) addition, and can act to suppress poly(A) site cleavage in a sequence-dependent manner. Elevated levels of CFI(m) suppressed cleavage at the primary poly(A) site of the pre-mRNA encoding the 68 kDa subunit of CFI(m). CFI(m)-mediated suppression of poly(A) site cleavage was dependent upon the presence of three copies of an RNA element initially identified by CFI(m)-SELEX. These data provide evidence for a mechanism for the regulation of poly(A) site selection by a basal pre-mRNA 3' processing factor."xsd:string
http://purl.uniprot.org/citations/14690600http://purl.org/dc/terms/identifier"doi:10.1016/s1097-2765(03)00453-2"xsd:string
http://purl.uniprot.org/citations/14690600http://purl.org/dc/terms/identifier"doi:10.1016/s1097-2765(03)00453-2"xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/author"Brown K.M."xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/author"Brown K.M."xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/author"Gilmartin G.M."xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/author"Gilmartin G.M."xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/name"Mol. Cell"xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/name"Mol. Cell"xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/pages"1467-1476"xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/pages"1467-1476"xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/title"A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im."xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/title"A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im."xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/14690600http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/14690600http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14690600
http://purl.uniprot.org/citations/14690600http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14690600
http://purl.uniprot.org/citations/14690600http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14690600
http://purl.uniprot.org/citations/14690600http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14690600
http://purl.uniprot.org/uniprot/O43809http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/14690600
http://purl.uniprot.org/uniprot/Q16630http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/14690600