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http://purl.uniprot.org/citations/14697234 | http://www.w3.org/2000/01/rdf-schema#comment | "In contrast to the classical HLA class Ia molecules, the nonclassical HLA-G primary transcript is alternatively spliced to generate several mRNAs that encode four membrane-bound and three soluble isoforms. This study demonstrated that the soluble form of HLA-G can also be generated by metalloproteinase-dependent shedding at post-translational level. These soluble HLA-G1 molecules generated by the cleavage of membrane-bound HLA-G1 associate with beta2-microglobulin and contain bound peptides that are stable at physiological conditions. This report further showed that the soluble HLA-G1 is able to protect HLA class I-negative K562 cells from NK lysis, suggesting that soluble HLA-G could act as an immunoregulator in NK cell recognition and possibly in other immune responses."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2003.11.153"xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/author | "Lee S."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/author | "Shin J."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/author | "Cho K."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/author | "Park B."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/author | "Ahn K."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/author | "Park G.M."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/pages | "606-611"xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/title | "Soluble HLA-G generated by proteolytic shedding inhibits NK-mediated cell lysis."xsd:string |
http://purl.uniprot.org/citations/14697234 | http://purl.uniprot.org/core/volume | "313"xsd:string |
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