| http://purl.uniprot.org/citations/14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14700596 | http://www.w3.org/2000/01/rdf-schema#comment | "Oligotyping performed among ethnically mixed Venezuelan patients with myasthenia gravis (MG) and controls has revealed positive associations of HLA class I A*31, B*08, B*39, B*40, C*15, C*17, and class II DRB1*09 and negative associations of DQB1*06 and DQA1*02 with the disease. Sequential removal of human leukocyte antigen B (HLA-B) alleles when relative predispositional effects (RPEs) were looked for demonstrated that B*08 is the allele group with the largest contribution in the overall MG patients followed by B*39 and B*40. Several specificities (A*31, B*08, C*17, DRB1*03, DQA1*05, and DQB1*02) indicated increased frequencies among patients with thymic hyperplasia versus patients without hyperplasia or controls. Tests to identify alleles with the strongest association to MG in our patients detected DRB1*13 and B*38 as possible predisposing secondarily associated alleles in patients with hyperplasia. The associations observed disappear after Bonferoni correction of probability values and have been described in patients of Caucasian and/or Oriental ethnic background. Thus, our results reflect the heterogeneity of our population and of the patients tested and suggest a limited influence of several HLA genes in this heterogeneous disease or that these might be only markers of nearby non-HLA genes responsible for the susceptibility or resistance effect."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.humimm.2003.10.003"xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/author | "Vargas V."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/author | "Layrisse Z."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/author | "Montagnani S."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/author | "Fernandez-Mestre M.T."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/author | "Cotua M."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/author | "Ogando V."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/name | "Hum Immunol"xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/pages | "54-59"xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/title | "HLA class II and class I polymorphism in Venezuelan patients with myasthenia gravis."xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://purl.uniprot.org/core/volume | "65"xsd:string |
| http://purl.uniprot.org/citations/14700596 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14700596 |
| http://purl.uniprot.org/citations/14700596 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-14700596 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14700596 |