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http://purl.uniprot.org/citations/14700598http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14700598http://www.w3.org/2000/01/rdf-schema#comment"Polymerase chain reaction-sequence-specific oligonucleotide probes typing methods have been applied to 1000 individuals from the Northern Ireland population to give human leukocyte antigen DRB1 (HLA-DRB1) allele assignment. HLA-DRB1 allele frequencies and four-locus haplotypes (A/B/C/DR) for this Caucasian population, based on HLA class I and class II allele assignment, are now presented. No significant deviations from Hardy-Weinberg proportions were observed. The HLA-C locus exhibited marginal evidence of selection (p<0.03, uncorrected one-sided test) in the direction of balancing selection; the HLA-A, -B, and -DRB1 allele frequency distributions were compatible with expectations under a neutral model (which does not mean that selection is not operating). Evidence for selection was seen on haplotypes HLA-A*010101-B*0801-DRB1*030101 and HLA-A*290201-B*440301-DRB1*070101 based on their patterns of linkage disequilibrium."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.org/dc/terms/identifier"doi:10.1016/j.humimm.2003.10.004"xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Meyer D."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Thomson G."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Middleton D."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Williams F."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Kelly P."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Lancaster A."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Meenagh A."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"McNally M."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Nelson M.P."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/author"Single R."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/name"Hum Immunol"xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/pages"66-77"xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/title"High resolution HLA-DRB1 identification of a Caucasian population."xsd:string
http://purl.uniprot.org/citations/14700598http://purl.uniprot.org/core/volume"65"xsd:string
http://purl.uniprot.org/citations/14700598http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/14700598
http://purl.uniprot.org/citations/14700598http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/14700598
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-14700598http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14700598
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-14700598http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14700598
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-14700598http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14700598
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-14700598http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14700598
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-14700598http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/14700598