| http://purl.uniprot.org/citations/14707112 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14707112 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14707112 | http://www.w3.org/2000/01/rdf-schema#comment | "The activator protein 1 (AP-1) transcription factor is a key participant in the control of T cell proliferation, cytokine production, and effector function. In the immune system, AP-1 activity is highest in T cells, suggesting that a subset of T cell-specific coactivator proteins exist to selectively potentiate AP-1 function. Here, we describe that the expression of Schnurri-3, also known as kappa recognition component (KRC), is induced upon T cell receptor signaling in T cells and functions to regulate the expression of the interleukin 2 (IL-2) gene. Overexpression of KRC in transformed and primary T cells leads to increased IL-2 production, whereas dominant-negative KRC, or loss of KRC protein in KRC-null mice, results in diminished IL-2 production. KRC physically associates with the c-Jun transcription factor and serves as a coactivator to augment AP-1-dependent IL-2 gene transcription."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.20030421"xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.20030421"xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/author | "Glimcher L.H."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/author | "Glimcher L.H."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/author | "Oukka M."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/author | "Oukka M."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/author | "Wein M.N."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/author | "Wein M.N."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/name | "J. Exp. Med."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/name | "J. Exp. Med."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/pages | "15-24"xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/pages | "15-24"xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/title | "Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/title | "Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells."xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/volume | "199"xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://purl.uniprot.org/core/volume | "199"xsd:string |
| http://purl.uniprot.org/citations/14707112 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14707112 |
| http://purl.uniprot.org/citations/14707112 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14707112 |
| http://purl.uniprot.org/citations/14707112 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14707112 |
| http://purl.uniprot.org/citations/14707112 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14707112 |