| http://purl.uniprot.org/citations/14712213 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14712213 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14712213 | http://www.w3.org/2000/01/rdf-schema#comment | "Chromosome 9, which is often partially or fully reduced to homozygosity in bladder cancer cells, harbors several tumor suppressor loci including deleted in bladder cancer chromosome region 1 (DBCCR1) at 9q32-33. To study DBCCR1 function, stable cell lines, inducible for DBCCR1 expression by tetracycline, were made, but the DBCCR1 protein was not expressed at detectable levels. To understand the fate of DBCCR1-expressing cells, human bladder tumor cells were transiently transfected with an expression vector containing DBCCR1 fused to enhanced green fluorescent protein (EGFP). Initially, DBCCR1-EGFP-expressing cells demonstrated diffuse cytoplasmic green fluorescence with nuclear exclusion patterns. After time, the intensity level of green fluorescence increased and a granular distribution of protein became visible in the cells. At this point, cells rounded up and detached from the tissue culture dish. Cells transfected with a control vector, containing only EGFP, and partial DBCCR1-EGFP fusion constructs did not demonstrate this behavior. DBCCR1-mediated cell death in cultured tumor cells was independent of caspase-3 activation and did not result in detectable DNA strand breaks by TUNEL staining that are hallmarks of the classical apoptotic pathway."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1206642"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1206642"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/author | "Messing E.M."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/author | "Messing E.M."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/author | "Reeder J.E."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/author | "Reeder J.E."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/author | "Wright K.O."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/author | "Wright K.O."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/pages | "82-90"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/pages | "82-90"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/title | "DBCCR1 mediates death in cultured bladder tumor cells."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/title | "DBCCR1 mediates death in cultured bladder tumor cells."xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/14712213 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14712213 |
| http://purl.uniprot.org/citations/14712213 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14712213 |
| http://purl.uniprot.org/citations/14712213 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14712213 |
| http://purl.uniprot.org/citations/14712213 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14712213 |