http://purl.uniprot.org/citations/14718045 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14718045 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously reported an association between the human leukocyte antigen (HLA) haplotype DRB1*1302-DQB1*0604 in the HLA class II region and non-obstructive azoospermia in Japanese men. To identify possible associations between the HLA-DRB1*1302-DQB1*0604 allele in the HLA class II region and azoospermia factor (AZF) deletion in the Y chromosome, we performed genomic polymerase chain reaction (PCR) analysis of the AZF region. We then determined spermatogenic impairment (Johnsen score) in testicular biopsy specimens from patients with or without the DRB1*1302-DQB1*0604 haplotype. The AZF microdeletion rate in patients with this haplotype was 3.85%, compared with 11.8% in others (no correlation). However, Johnsen scores in patients with the DRB1*1302-DQB1*0604 haplotype were 3.13 +/- 1.34 (mean +/- SD), compared with 3.70 +/-1.51 in others (p < 0.05). While the DRB1*1302-DQB1*0604 haplotype acts independently from Y chromosome deletion, the haplotype might either act directly, or be functionally related to an unknown autosomal gene. In either case, this haplotype showed association with severe spermatogenic impairment."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.0105-6263.2003.00445.x"xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Yamada K."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Takao T."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Koga M."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Miyagawa Y."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Okuyama A."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Tsujimura A."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Takahara S."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Matsumiya K."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Goto R."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/author | "Sada M."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/name | "Int J Androl"xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/pages | "37-41"xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/title | "Susceptibility gene for non-obstructive azoospermia in the HLA class II region: correlations with Y chromosome microdeletion and spermatogenesis."xsd:string |
http://purl.uniprot.org/citations/14718045 | http://purl.uniprot.org/core/volume | "27"xsd:string |
http://purl.uniprot.org/citations/14718045 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14718045 |
http://purl.uniprot.org/citations/14718045 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14718045 |
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http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-14718045 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14718045 |
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-14718045 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14718045 |
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-14718045 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14718045 |
http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-14718045 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14718045 |