http://purl.uniprot.org/citations/14720597 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14720597 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14720597 | http://www.w3.org/2000/01/rdf-schema#comment | "A Xenopus laevis egg cortical granule, calcium-dependent, galactosyl-specific lectin participates in forming the fertilization layer of the egg envelope and functions in establishing a block to polyspermy. We report the cDNA cloning of the lectin, expression of the cortical granule lectin gene during oogenesis and early development, and identification of a new family of lectins. The translated cDNA for the cortical granule lectin had a signal peptide, a structural sequence of 298 amino acids, a molecular weight of 32.7 K, contained consensus sequence sites for N-glycosylation and a fibrinogen domain. The lectin cDNA was expressed during early stages of oogenesis. Lectin glycoprotein levels were constant during development with 2/3 of the lectin associated with the extracellular perivitelline space and the egg/embryo fertilization envelope. Lectin mRNA levels were from 100-to 1000-fold greater in ovary than in other adult tissues. The lectin had no sequence homology to the previously identified lectin families. The lectin had 41-88% amino acid identity with nine translated cDNA sequences from an ascidian, lamprey, frog, mouse, and human. Based on the conserved carbohydrate binding and structural properties of these glycoproteins, we propose a new family of lectins, the eglectin family."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1095-6433(03)00269-1"xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1095-6433(03)00269-1"xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.org/dc/terms/identifier | "doi:10.1016/S1095-6433(03)00269-1"xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Hedrick J.L."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Hedrick J.L."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Chang B.Y."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Chang B.Y."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Peavy T.R."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Peavy T.R."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Wardrip N.J."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/author | "Wardrip N.J."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/name | "Comp. Biochem. Physiol."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/name | "Comp. Biochem. Physiol."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/pages | "115-129"xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/pages | "115-129"xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/title | "The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/title | "The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins."xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/volume | "137A"xsd:string |
http://purl.uniprot.org/citations/14720597 | http://purl.uniprot.org/core/volume | "137A"xsd:string |
http://purl.uniprot.org/citations/14720597 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14720597 |