| http://purl.uniprot.org/citations/14731280 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14731280 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14731280 | http://www.w3.org/2000/01/rdf-schema#comment | "The csiD-ygaF-gabDTP region in the Escherichia coli genome represents a cluster of sigma S-controlled genes. Here, we investigated promoter structures, sigma factor dependencies, potential co-regulation and environmental regulatory patterns for all of these genes. We find that this region constitutes a complex operon with expression being controlled by three differentially regulated promoters: (i) csiDp, which affects the expression of all five genes, is cAMP-CRP/sigma S-dependent and activated exclusively upon carbon starvation and stationary phase; (ii) gabDp1, which is sigma S-dependent and exhibits multiple stress induction like sigma S itself; and (iii) gabDp2[previously suggested by Schneider, B.L., Ruback, S., Kiupakis, A.K., Kasbarian, H., Pybus, C., and Reitzer, L. (2002) J. Bacteriol. 184: 6976-6986], which appears to be Nac/sigma 70-controlled and to respond to poor nitrogen sources. In addition, we identify a novel repressor, CsiR, which modulates csiDp activity in a temporal manner during early stationary phase. Finally, we propose a physiological role for sigma S-controlled GabT/D-mediated gamma-aminobutyrate (GABA) catabolism and glutamate accumulation in general stress adaptation. This physiological role is reflected by the activation of the operon-internal gabDp1 promoter under the different conditions that also induce sigma S, which include shifts to acidic pH or high osmolarity as well as starvation or stationary phase."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2958.2003.03867.x"xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2958.2003.03867.x"xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/author | "Metzner M."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/author | "Metzner M."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/author | "Hengge R."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/author | "Hengge R."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/author | "Germer J."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/author | "Germer J."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/pages | "799-811"xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/pages | "799-811"xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/title | "Multiple stress signal integration in the regulation of the complex sigma S-dependent csiD-ygaF-gabDTP operon in Escherichia coli."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/title | "Multiple stress signal integration in the regulation of the complex sigma S-dependent csiD-ygaF-gabDTP operon in Escherichia coli."xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/volume | "51"xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://purl.uniprot.org/core/volume | "51"xsd:string |
| http://purl.uniprot.org/citations/14731280 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14731280 |
| http://purl.uniprot.org/citations/14731280 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14731280 |
| http://purl.uniprot.org/citations/14731280 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14731280 |
| http://purl.uniprot.org/citations/14731280 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14731280 |