| http://purl.uniprot.org/citations/14732704 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14732704 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14732704 | http://www.w3.org/2000/01/rdf-schema#comment | "S1P(1) is a widely distributed G protein-coupled receptor whose ligand, sphingosine 1-phosphate, is present in high concentrations in the blood. The sphingosine 1-phosphate receptor-signaling pathway is believed to have potent effects on cell trafficking in the immune system. To determine the precise role of the S1P(1) receptor on T-cells, we established a T-cell-specific S1P(1) knock-out mouse. The mutant mice showed a block in the egress of mature T-cells into the periphery. The expression of the S1P(1) receptor was up-regulated in mature thymocytes, and its deletion altered the chemotactic responses of thymocytes to sphingosine 1-phosphate. The results indicated that the expression of the S1P(1) receptor on T-cells controls their exit from the thymus and entry into the blood and, thus, has a central role in regulating the numbers of peripheral T-cells."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m314291200"xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m314291200"xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Proia R.L."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Proia R.L."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Allende M.L."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Allende M.L."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Dreier J.L."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Dreier J.L."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Mandala S."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/author | "Mandala S."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/pages | "15396-15401"xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/pages | "15396-15401"xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/title | "Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/title | "Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration."xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/volume | "279"xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://purl.uniprot.org/core/volume | "279"xsd:string |
| http://purl.uniprot.org/citations/14732704 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14732704 |
| http://purl.uniprot.org/citations/14732704 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14732704 |