| http://purl.uniprot.org/citations/14749726 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14749726 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14749726 | http://www.w3.org/2000/01/rdf-schema#comment | "Here we report on a lipid-signalling pathway in plants that is downstream of phosphatidic acid and involves the Arabidopsis protein kinase, AGC2-1, regulated by the 3'-phosphoinositide-dependent kinase-1 (AtPDK1). AGC2-1 specifically interacts with AtPDK1 through a conserved C-terminal hydrophobic motif that leads to its phosphorylation and activation, whereas inhibition of AtPDK1 expression by RNA interference abolishes AGC2-1 activity. Phosphatidic acid specifically binds to AtPDK1 and stimulates AGC2-1 in an AtPDK1-dependent manner. AtPDK1 is ubiquitously expressed in all plant tissues, whereas expression of AGC2-1 is abundant in fast-growing organs and dividing cells, and activated during re-entry of cells into the cell cycle after sugar starvation-induced G1-phase arrest. Plant hormones, auxin and cytokinin, synergistically activate the AtPDK1-regulated AGC2-1 kinase, indicative of a role in growth and cell division. Cellular localisation of GFP-AGC2-1 fusion protein is highly dynamic in root hairs and at some stages confined to root hair tips and to nuclei. The agc2-1 knockout mutation results in a reduction of root hair length, suggesting a role for AGC2-1 in root hair growth and development."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.emboj.7600068"xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.emboj.7600068"xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Anthony R.G."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Anthony R.G."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Koncz C."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Koncz C."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Munnik T."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Munnik T."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Testerink C."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Testerink C."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Deak M."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Deak M."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Boegre L."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Boegre L."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Henriques R."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Henriques R."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Helfer A."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Helfer A."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Rios G."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Rios G."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Meszaros T."xsd:string |
| http://purl.uniprot.org/citations/14749726 | http://purl.uniprot.org/core/author | "Meszaros T."xsd:string |