| http://purl.uniprot.org/citations/14760938 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14760938 | http://www.w3.org/2000/01/rdf-schema#comment | "The aim of our study was to analyse a significance of tumour necrosis factor (TNF)-alpha promoter gene polymorphisms in relation to the HLA-DR locus in genetic predisposition to pemphigus. TNF-alpha gene polymorphisms in position -238 and -308 were identified using a modified polymerase chain reaction-restriction fragment length polymorphism method in 53 patients with pemphigus (38 with pemphigus vulgaris, 15 with pemphigus foliaceus) and 87 healthy controls. The HLA-DRB1 locus was typed using the polymerase chain reaction SSO method in all the patients and 152 population controls. Carriers of the TNF-alpha polymorphic -308 A allele were found to be more frequent in the pemphigus foliaceus group in comparison with the control group (odds ratio (OR) = 8.12; p = 0.0005). A significant association between HLA-DRB1*04 (OR = 3.86; pcor = 0.0001) and DRB1*14 (OR = 8.4; pcor = 0.0001) and pemphigus vulgaris was found. In this group of patients a decreased frequency of HLA-DRB1*07 (OR = 0.08; pcor = 0.006) was also identified. We have shown for the first time a positive association of TNF-alpha polymorphism in position -308 with pemphigus foliaceus."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.org/dc/terms/identifier | "doi:10.1080/09629350310001619735"xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/author | "Borowiec M."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/author | "Woszczek G."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/author | "Kowalski M.L."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/author | "Narbutt J."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/author | "Ptasinska A."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/author | "Sysa-Jedrzejowska A."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/author | "Torzecka J.D."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/name | "Mediators Inflamm"xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/pages | "303-307"xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/title | "Tumour necrosis factor-alpha polymorphism as one of the complex inherited factors in pemphigus."xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/14760938 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14760938 |
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