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http://purl.uniprot.org/citations/14764704http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14764704http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14764704http://www.w3.org/2000/01/rdf-schema#comment"In an effort to characterize molecules with immunoregulatory potential, we raised mAbs to human dendritic cells. We selected an Ab that recognizes a molecule that is induced on monocytes differentiated in vitro toward dendritic cells. Retroviral expression cloning identified this molecule as B7-H3, a member of the B7 family described recently. In contrast to an earlier report, in which B7-H3 was described as a molecule consisting of two Ig-like domains, our cDNA encoded a type I membrane protein with four Ig-like domains, and the molecule identified by us was therefore named 4Ig-B7-H3. mRNA analysis as well as Western blotting experiments performed by us did not reveal evidence for a small B7-H3. B7-H3 is not expressed on peripheral blood lymphocytes, monocytes, or granulocytes. Upon in vitro stimulation, the expression of B7-H3 is induced on T cells, B cells, and NK cells. A number of different approaches were used to investigate the function of human B7-H3. In contrast to an earlier report, our data do not support a costimulatory role of B7-H3 in anti-CD3-mediated activation of the TCR-complex resulting in T cell proliferation and IFN-gamma production."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.org/dc/terms/identifier"doi:10.4049/jimmunol.172.4.2352"xsd:string
http://purl.uniprot.org/citations/14764704http://purl.org/dc/terms/identifier"doi:10.4049/jimmunol.172.4.2352"xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Kirchberger S."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Kirchberger S."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Majdic O."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Majdic O."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Knapp W."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Knapp W."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Steinberger P."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Steinberger P."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Stockl J."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Stockl J."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Derdak S.V."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Derdak S.V."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Klauser C."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Klauser C."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Pfistershammer K."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Pfistershammer K."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Pickl W.F."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Pickl W.F."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Zlabinger G."xsd:string
http://purl.uniprot.org/citations/14764704http://purl.uniprot.org/core/author"Zlabinger G."xsd:string