RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/1489724http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1489724http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1489724http://www.w3.org/2000/01/rdf-schema#comment"A novel mouse gene, Enhancer trap locus 1 (Etl-1), was identified in close proximity to a lacZ enhancer trap integration in the mouse genome showing a specific beta-galactosidase staining pattern during development. In situ analysis revealed a widespread but not ubiquitous expression of Etl-1 throughout development with particularly high levels in the central nervous system and epithelial cells. The amino acid sequence of the Etl-1 protein deduced from the cDNA shows strong similarity, over a stretch of 500 amino acids, to the Drosophila brahma protein involved in the regulation of homeotic genes and to the yeast transcriptional activator protein SNF2/SWI2 as well as to the RAD54 protein and the recently described helicase-related yeast proteins STH1 and MOT1. Etl-1 is the first mammalian member of this group of proteins that are implicated in gene regulation and/or influencing chromatin structure. The homology to the regulatory proteins SNF2/SWI2 and brahma and the expression pattern during embryogenesis suggest that Etl-1 protein might be involved in gene regulating pathways during mouse development."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.org/dc/terms/identifier"doi:10.1016/0925-4773(92)90030-n"xsd:string
http://purl.uniprot.org/citations/1489724http://purl.org/dc/terms/identifier"doi:10.1016/0925-4773(92)90030-n"xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Rossant J."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Rossant J."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Gossler A."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Gossler A."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Kisters-Woike B."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Kisters-Woike B."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Soininen R."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Soininen R."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Schoor M."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Schoor M."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Henseling U."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Henseling U."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Tepe C."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/author"Tepe C."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/date"1992"xsd:gYear
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/name"Mech. Dev."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/name"Mech. Dev."xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/pages"111-123"xsd:string
http://purl.uniprot.org/citations/1489724http://purl.uniprot.org/core/pages"111-123"xsd:string