http://purl.uniprot.org/citations/14980718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/14980718 | http://www.w3.org/2000/01/rdf-schema#comment | "The human forkhead box O1A (FOXO1A) gene belongs to the human forkhead gene family and acts downstream of the human insulin signalling pathway. In this study, polymorphisms of the Intron I of FOXO1A gene were studied in Italian healthy people and insulin resistant subjects. No significant association between the germ-line variability in the Intron I of FOXO1A and insulin resistance was observed. Interestingly, during the study, a new 39-bp sequence insertion polymorphism in Intron I of FOXO1A gene was described. The polymorphism was found to co-segregate in a co-dominant Mendelian fashion and to be present in an ethnically distinct population (Greeks). A BLAST search showed that the sequence shares 100% identity with a mtDNA (mitochondrial DNA) sequence coding for the ATP synthase 8 (ATPase8) and ATP synthase 6 (ATPase6) genes. Hence, FOXO1A Intron I is a polymorphic nuclear region involved in the exchange of DNA material between mitochondrial and genomic DNA, which is a well-established mechanism of evolutionary change in eukaryotes."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.gene.2003.11.003"xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Olivieri F."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Franceschi C."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Gonos E.S."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Petropoulou C."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Cardelli M."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Marchegiani F."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Boemi M."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Testa R."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Bonafe M."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Carrieri G."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Cavallone L."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Giovagnetti S."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Lisa R."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Giampieri C."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Mugianesi E."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Centurelli M."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/author | "Cenerelli S."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/pages | "215-219"xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/title | "A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene."xsd:string |
http://purl.uniprot.org/citations/14980718 | http://purl.uniprot.org/core/volume | "327"xsd:string |