| http://purl.uniprot.org/citations/14988722 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14988722 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14988722 | http://www.w3.org/2000/01/rdf-schema#comment | "An animal's ability to detect and avoid toxic compounds in the environment is crucial for survival. We show that the nematode Caenorhabditis elegans avoids many water-soluble substances that are toxic and that taste bitter to humans. We have used laser ablation and a genetic cell rescue strategy to identify sensory neurons involved in the avoidance of the bitter substance quinine, and found that ASH, a polymodal nociceptive neuron that senses many aversive stimuli, is the principal player in this response. Two G protein alpha subunits GPA-3 and ODR-3, expressed in ASH and in different, nonoverlapping sets of sensory neurons, are necessary for the response to quinine, although the effect of odr-3 can only be appreciated in the absence of gpa-3. We identified and cloned a new gene, qui-1, necessary for quinine and SDS avoidance. qui-1 codes for a novel protein with WD-40 domains and which is expressed in the avoidance sensory neurons ASH and ADL."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.emboj.7600107"xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.emboj.7600107"xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Plasterk R.H."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Plasterk R.H."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Arbucci S."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Arbucci S."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Bazzicalupo P."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Bazzicalupo P."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Hilliard M.A."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Hilliard M.A."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Bergamasco C."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/author | "Bergamasco C."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/pages | "1101-1111"xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/pages | "1101-1111"xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/title | "Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/title | "Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans."xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/14988722 | http://purl.uniprot.org/core/volume | "23"xsd:string |