| http://purl.uniprot.org/citations/14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14991600 | http://www.w3.org/2000/01/rdf-schema#comment | "CD4+ alpha beta T cell populations that develop in mice deficient in MHC class II (through 'knockout' of either the Aalpha, or the Abeta chain of the I-A(b) molecule) comprise a major 'single-positive' (SP) CD4+ CD8-subset (60-90%) and a minor 'double-positive' (DP) CD4+ CD8alpha beta+ subset (10-40%). Many DP T cells found in spleen, mesenteric lymph nodes (MLN) and colonic lamina propria (cLP) express CD25, CD103 and Foxp3. Adoptive transfer of SP but not DP T cells from Aalpha(-/-) or Abeta(-/-) B6 mice into congenic RAG(-/-) hosts induces colitis. Transfer of SP T cells repopulates the host with only SP T cells; transfer of DP T cells repopulates the host with DP and SP T cells. Anti-CD25 antibody treatment of mice transplanted with DP T cells induces severe, lethal colitis; anti-CD25 antibody treatment of mice transplanted with SP T cells further aggravates the course of severe colitis. Hence, regulatory CD25+ T cells within (or developing from) the DP T cell population of MHC class II-deficient mice control the colitogenic potential of CD25- CD4+ T cells."xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.200324463"xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/author | "Reimann J."xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/author | "Leithauser F."xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/author | "Krajina T."xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/name | "Eur J Immunol"xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/pages | "705-714"xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/title | "MHC class II-independent CD25+ CD4+ CD8alpha beta+ alpha beta T cells attenuate CD4+ T cell-induced transfer colitis."xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://purl.uniprot.org/core/volume | "34"xsd:string |
| http://purl.uniprot.org/citations/14991600 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14991600 |
| http://purl.uniprot.org/citations/14991600 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14991600 |
| http://purl.uniprot.org/uniprot/#_A0A068BD71-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_A0A068BER6-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_A0A1D8M9B3-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_A0A1D8M9B5-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_A0A494B9G5-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_A0A494B9U2-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_G3UWR9-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_P04227-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_P04228-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_P06342-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_P06343-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |
| http://purl.uniprot.org/uniprot/#_P06345-mappedCitation-14991600 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14991600 |