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http://purl.uniprot.org/citations/15012983http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15012983http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15012983http://www.w3.org/2000/01/rdf-schema#comment"Substituted 3-amino-2-hydroxyamides and related hydroxyamides and acylhydrazines were identified as inhibitors of human methionine aminopeptidase-2 (MetAP2). Examination of substituents through parallel synthesis and iterative structure-based design allowed the identification of potent inhibitors with good selectivity against MetAP1. Diacylhydrazine 3t (A-357300) was identified as an analogue displaying inhibition of methionine processing and cellular proliferation in human microvascular endothelial cells (HMVEC)."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2003.12.031"xsd:string
http://purl.uniprot.org/citations/15012983http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2003.12.031"xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Kim K.H."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Kim K.H."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Park C."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Park C."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Wang J."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Wang J."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Yang F."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Yang F."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Kawai M."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Kawai M."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Patel J."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Patel J."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Craig R.A."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Craig R.A."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Sheppard G.S."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Sheppard G.S."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Henkin J."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Henkin J."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Lesniewski R."xsd:string
http://purl.uniprot.org/citations/15012983http://purl.uniprot.org/core/author"Lesniewski R."xsd:string