| http://purl.uniprot.org/citations/15014079 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15014079 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15014079 | http://www.w3.org/2000/01/rdf-schema#comment | "Defects in human DNA mismatch repair predispose to cancer, but many components of the pathway have not been identified. We report here the identification and characterization of a novel component required for mismatch repair in human cells. A 30-kDa protein was purified to homogeneity by virtue of its ability to complement a depleted HeLa extract in repair of mismatched heteroduplexes. The complementing activity was identified as HMGB1 (the high mobility group box 1 protein), a non-histone chromatin protein that facilitates protein-protein interactions and recognizes DNA damage. Evidence is also presented that HMGB1 physically interacts with MutSalpha and is required at a step prior to the excision of mispaired nucleotide in mismatch repair."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m401931200"xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m401931200"xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Gu L."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Gu L."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Guo S."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Guo S."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Wang C."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Wang C."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Yuan F."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Yuan F."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Li G.M."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/author | "Li G.M."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/pages | "20935-20940"xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/pages | "20935-20940"xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/title | "Evidence for involvement of HMGB1 protein in human DNA mismatch repair."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/title | "Evidence for involvement of HMGB1 protein in human DNA mismatch repair."xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/volume | "279"xsd:string |
| http://purl.uniprot.org/citations/15014079 | http://purl.uniprot.org/core/volume | "279"xsd:string |