| http://purl.uniprot.org/citations/15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15020226 | http://www.w3.org/2000/01/rdf-schema#comment | "The MUC1 tumor antigen is overexpressed on most breast tumors and metastases. It interacts with signaling proteins such as the ErbB kinases and beta-catenin, and is involved in mammary gland oncogenesis and tumor progression. Herein, we report a novel interaction between MUC1 and adenomatous polyposis coli (APC), a tumor suppressor involved in downregulating beta-catenin signaling. Initially identified in colorectal cancer, APC is also downregulated in breast tumors and presumably involved in mammary carcinogenesis. MUC1 and APC co-immunoprecipitate from the ZR-75-1 human breast carcinoma cell line and co-localize in mouse mammary glands and tumors. These studies also indicate that the association of MUC1 and APC may be increased by epidermal growth factor stimulation. Intriguingly, the co-immunoprecipitation of MUC1 and APC increases in human breast tumors and metastases as compared to adjacent normal tissues, indicating that this association may play a role in the formation and progression of breast tumors."xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2004.02.072"xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/author | "Hansson G.C."xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/author | "Fernandez-Rodriguez J."xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/author | "Gendler S.J."xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/author | "Schroeder J.A."xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/author | "Hattrup C.L."xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/pages | "364-369"xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/title | "MUC1 can interact with adenomatous polyposis coli in breast cancer."xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://purl.uniprot.org/core/volume | "316"xsd:string |
| http://purl.uniprot.org/citations/15020226 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15020226 |
| http://purl.uniprot.org/citations/15020226 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15020226 |
| http://purl.uniprot.org/uniprot/#_A0A1Y6IM53-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A0A1Y6IM71-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A0A1Y6IM94-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A0A384ME03-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A0A224ANK2-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A0A386AVV0-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A0A224AV41-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A5JUM6-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A5JUM7-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |
| http://purl.uniprot.org/uniprot/#_A5JUM8-mappedCitation-15020226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15020226 |