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http://purl.uniprot.org/citations/15028282http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15028282http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15028282http://www.w3.org/2000/01/rdf-schema#comment"This study established the utility of cross-species application of the cDNA microarray technique for investigating differential gene expression. Using both total RNA and mRNA samples recovered from two opossum cell lines derived from UVB-induced melanoma, we analyzed expression of ca. 4400 genes on the human DermArray DNA microarrays. The signals generated on the DermArrays were clear, strong, and reproducible. A cDNA dot blot consisting of differentially expressed genes representative of different functional clusters was used to validate the DermArray results. We also cloned a Monodelphis gene, keratin 18 (KRT18), and characterized its expression patterns in tumor samples of different progression stages. Up-regulated expression was observed for the KRT18 gene in advanced melanomas, a finding consistent with the DermArray analysis. These results provide evidence that cross-species application of cDNA microarrays is a useful strategy for investigating gene expression patterns in animal models for which species-specific cDNA microarrays are not available."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.org/dc/terms/identifier"doi:10.1016/j.ygeno.2003.10.007"xsd:string
http://purl.uniprot.org/citations/15028282http://purl.org/dc/terms/identifier"doi:10.1016/j.ygeno.2003.10.007"xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Wang Z."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Wang Z."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Davis R.L."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Davis R.L."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"VandeBerg J.L."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"VandeBerg J.L."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Dooley T.P."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Dooley T.P."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Curto E.V."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/author"Curto E.V."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/pages"588-599"xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/pages"588-599"xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/title"Cross-species application of cDNA microarrays to profile gene expression using UV-induced melanoma in Monodelphis domestica as the model system."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/title"Cross-species application of cDNA microarrays to profile gene expression using UV-induced melanoma in Monodelphis domestica as the model system."xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/volume"83"xsd:string
http://purl.uniprot.org/citations/15028282http://purl.uniprot.org/core/volume"83"xsd:string