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http://purl.uniprot.org/citations/15039132http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15039132http://www.w3.org/2000/01/rdf-schema#comment"

Aims

The study evaluated the relationship between cardiovascular risk factors (CRF), gene polymorphism, calcification and fibrosis of stenotic aortic valves.

Methods and results

The calcium content of 187 excised stenotic aortic valves was determined using atomic absorption spectroscopy. Hydroxyproline content was quantified. Left-heart catheterization was performed. CRF and genotypes of the interleukin 10, connective tissue growth factor (CTGF) and chemokine receptor 5 (CCR5) polymorphisms were assessed. Calcification consisted of Ca-deficient hexagonal hydroxyapatite, Ca(10 - x)(HPO4)x(PO4)(6 - x)(OH)(2 - x); with 0ConclusionCalcification of stenotic aortic valves consists of Ca-deficient hexagonal hydroxyapatite. Gender and genetic polymorphisms have an impact on the degree of aortic valve calcification."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.org/dc/terms/identifier"doi:10.1016/j.ehj.2003.09.006"xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Weiss S."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Weber C."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Hoffmann R."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Zerres K."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Schmitz F."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Ortlepp J.R."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Hanrath P."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Mevissen V."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Autschbach R."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Dronskowski R."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Huster J."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/author"Langebartels G."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/name"Eur Heart J"xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/pages"514-522"xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/title"The amount of calcium-deficient hexagonal hydroxyapatite in aortic valves is influenced by gender and associated with genetic polymorphisms in patients with severe calcific aortic stenosis."xsd:string
http://purl.uniprot.org/citations/15039132http://purl.uniprot.org/core/volume"25"xsd:string
http://purl.uniprot.org/citations/15039132http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15039132
http://purl.uniprot.org/citations/15039132http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15039132
http://purl.uniprot.org/uniprot/#_A0A089G6S9-mappedCitation-15039132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15039132
http://purl.uniprot.org/uniprot/#_A0A089G7F7-mappedCitation-15039132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15039132
http://purl.uniprot.org/uniprot/#_A0A089G7G0-mappedCitation-15039132http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15039132
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