DESCRIBE <http://purl.uniprot.org/citations/15042023>

Subject	Predicate	Object
http://purl.uniprot.org/citations/15042023	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15042023	http://www.w3.org/2000/01/rdf-schema#comment	" Objective The purpose of this study was to investigate the expression of matrix metalloproteinase-8 by human fetal membranes during labor. Study design Fetal membranes were obtained from women who underwent normal labor or elective cesarean delivery at term. Matrix metalloproteinase-8 levels in fetal membranes were determined by enzyme-linked immunosorbent assay and Western blot; the expression of the matrix metalloproteinase-8 gene was detected by reverse transcription-polymerase chain reaction. Immunohistochemistry and in situ hybridization was performed to localize matrix metalloproteinase-8 protein and messenger RNA in intact membranes. Results Matrix metalloproteinase-8 protein levels were increased 5-fold in fetal membranes from labor compared with membranes that were obtained from cesarean delivery. Western blots confirmed the presence of matrix metalloproteinase-8 in protein extracts. Reverse transcription-polymerase chain reaction, in situ hybridization, and immunohistochemistry demonstrated that matrix metalloproteinase-8 messenger RNA and protein were expressed almost exclusively in the chorion after labor. Conclusion We conclude that matrix metalloproteinase-8 is produced primarily by chorionic cells in human fetal membranes and that the level of matrix metalloproteinase-8 protein and messenger RNA expression in fetal membranes increases during labor."xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.org/dc/terms/identifier	"doi:10.1016/j.ajog.2003.09.032"xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/author	"Marciano D."xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/author	"Parry S."xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/author	"Diaz-Cueto L."xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/author	"Arechavaleta-Velasco F."xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/date	"2004"xsd:gYear
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/name	"Am J Obstet Gynecol"xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/pages	"843-850"xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/title	"Matrix metalloproteinase-8 is expressed in human chorion during labor."xsd:string
http://purl.uniprot.org/citations/15042023	http://purl.uniprot.org/core/volume	"190"xsd:string
http://purl.uniprot.org/citations/15042023	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/15042023
http://purl.uniprot.org/citations/15042023	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/15042023
http://purl.uniprot.org/uniprot/#_A8K9E4-mappedCitation-15042023	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15042023
http://purl.uniprot.org/uniprot/#_B4E0T0-mappedCitation-15042023	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15042023
http://purl.uniprot.org/uniprot/#_B4E0I2-mappedCitation-15042023	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15042023
http://purl.uniprot.org/uniprot/#_P22894-mappedCitation-15042023	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/15042023
http://purl.uniprot.org/uniprot/A8K9E4	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/15042023
http://purl.uniprot.org/uniprot/B4E0T0	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/15042023
http://purl.uniprot.org/uniprot/B4E0I2	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/15042023
http://purl.uniprot.org/uniprot/P22894	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/15042023