http://purl.uniprot.org/citations/15064728 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15064728 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15064728 | http://www.w3.org/2000/01/rdf-schema#comment | "The CCAAT enhancer binding protein epsilon (C/EBP-epsilon) transcription factor is expressed predominantly in granulocytes. Mice with a disruption of the C/EBP-epsilon gene fail to produce mature granulocytes and eosinophils. Cells derived from the peritoneal exudates of C/EBP-epsilon -/-mice lack the expression of a number of chemokines and chemokine receptor genes. We have found a novel C/EBP-epsilon-dependent promyelocyte-specific gene, mXCP1. mXCP1 belongs to a family of XCP/FIZZ/Resistin genes, which includes four murine genes and two human genes, hXCP1 and hXCP2. These genes have four exons and encode short secreted proteins sharing a ten-cysteine motif. Murine mXCP1, mXCP2 and mXCP3 genes map to murine chromosome 16 and mXCP4 is positioned on chromosome 8; the hXCP1 and hXCP2 genes are located at homologous regions of chromosomes 3 and 19. Introduction of an inducible C/EBP-epsilon gene into the NIH3T3 and myeloid cells from C/EBP-epsilon-null mice line revealed that the conditional expression of C/EBP-epsilon induced mXCP1. The HXCP1 gene was identified as a C/EBP-epsilon-dependent regulatory homologue of mXCP1. The expression data for other members of XCP/FIZZ gene family are presented. Further studies indicate that XCP1 is a secreted protein that is chemotactic to myeloid cells from C/EBP-epsilon-null mice and is able to interact directly with alpha-defensin."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1207126"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1207126"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Kubota T."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Kubota T."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Walter S."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Walter S."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Koeffler H.P."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Koeffler H.P."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Chumakov A.M."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/author | "Chumakov A.M."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/pages | "3414-3425"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/pages | "3414-3425"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/title | "Identification of murine and human XCP1 genes as C/EBP-epsilon-dependent members of FIZZ/Resistin gene family."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/title | "Identification of murine and human XCP1 genes as C/EBP-epsilon-dependent members of FIZZ/Resistin gene family."xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/volume | "23"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://purl.uniprot.org/core/volume | "23"xsd:string |
http://purl.uniprot.org/citations/15064728 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15064728 |
http://purl.uniprot.org/citations/15064728 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15064728 |