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http://purl.uniprot.org/citations/15068795http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15068795http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15068795http://www.w3.org/2000/01/rdf-schema#comment"The class A and class B synMuv genes are functionally redundant negative regulators of a Ras signaling pathway that induces C. elegans vulval development. A number of class B synMuv genes encode components of an Rb and histone deacetylase complex that likely acts to repress transcription of genes required for vulval induction. We discovered a new class of synMuv genes that acts redundantly with both the A and B classes of genes in vulval cell-fate determination. These new class C synMuv genes encode TRRAP, MYST family histone acetyltransferase, and Enhancer of Polycomb homologs, which form a putative C. elegans Tip60/NuA4-like histone acetyltransferase complex. A fourth gene with partial class C synMuv properties encodes a homolog of the mammalian SWI/SNF family ATPase p400. Our findings indicate that the coordinated action of two chromatin-modifying complexes, one with histone deacetylase and the other with histone acetyltransferase activity, is important in regulating Ras signaling and specifying cell fates during C. elegans development."xsd:string
http://purl.uniprot.org/citations/15068795http://purl.org/dc/terms/identifier"doi:10.1016/s1534-5807(04)00065-6"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.org/dc/terms/identifier"doi:10.1016/s1534-5807(04)00065-6"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.org/dc/terms/identifier"doi:10.1016/S1534-5807(04)00065-6"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/author"Horvitz H.R."xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/author"Horvitz H.R."xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/author"Ceol C.J."xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/author"Ceol C.J."xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/name"Dev. Cell"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/name"Dev. Cell"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/pages"563-576"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/pages"563-576"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/title"A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling."xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/title"A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling."xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/15068795http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/15068795http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15068795
http://purl.uniprot.org/citations/15068795http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15068795
http://purl.uniprot.org/citations/15068795http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15068795
http://purl.uniprot.org/citations/15068795http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15068795
http://purl.uniprot.org/uniprot/G5EEV2http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/15068795