| http://purl.uniprot.org/citations/15077163 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15077163 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15077163 | http://www.w3.org/2000/01/rdf-schema#comment | "Several genes that contain the PR (PRDI-BF1 and RIZ) domain have been linked with human cancers. We describe here a new PR-domain-containing gene designated as PRDM5 (PFM2). A PRDM5 cDNA was isolated based on its homology to the PR domain of RIZ1 (PRDM2). The gene encodes an open reading frame of 630 amino acids and contains a PR domain in the NH-terminal region followed by 16 zinc finger motifs. Radiation hybrid analysis mapped PRDM5 to human chromosome 4q26, a region thought to harbor tumor suppressor genes for breast, ovarian, liver, lung, colon, and other cancers. The gene has a CpG island promoter and is silenced in human breast, ovarian, and liver cancers. A recombinant adenovirus expressing PRDM5 caused G2/M arrest and apoptosis upon infection of tumor cells. These results suggest that inactivation of PRDM5 may play a role in carcinogenesis."xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1207615"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.onc.1207615"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/author | "Huang S."xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/author | "Huang S."xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/author | "Deng Q."xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/author | "Deng Q."xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/pages | "4903-4910"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/pages | "4903-4910"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/title | "PRDM5 is silenced in human cancers and has growth suppressive activities."xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/title | "PRDM5 is silenced in human cancers and has growth suppressive activities."xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/15077163 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15077163 |
| http://purl.uniprot.org/citations/15077163 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15077163 |
| http://purl.uniprot.org/citations/15077163 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15077163 |
| http://purl.uniprot.org/citations/15077163 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15077163 |
| http://purl.uniprot.org/uniprot/Q9NQX1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15077163 |
| http://purl.uniprot.org/embl-cds/AAF78077.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/15077163 |