http://purl.uniprot.org/citations/15081617 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15081617 | http://www.w3.org/2000/01/rdf-schema#comment | "Natural Killer T (NKT) cells in mice are generally defined as NK1.1(+) T cells, although NK1.1 antigen is expressed only in C57BL/6 and related strains. This has precluded investigations of other strains. To find a novel NKT cell surface marker, we generated a monoclonal antibody (mAb), U5A2-13, which recognizes phenotypically and functionally similar populations to NKT cells in naïve mice irrespective of strain. Here, by using a COS-7 expressional cloning system, we molecularly cloned a cDNA encoding a protein reactive with the U5A2-13 mAb and then identified it as intercellular adhesion molecule-1 (ICAM-1). Importantly, the U5A2-13 mAb did not stain hepatic mononuclear cells from ICAM-1 gene disrupted mice. Furthermore, Pepscan method disclosed that the discontinuous epitope for U5A2-13 mAb is composed of three loops located in extracellular domain two of ICAM-1. Overall, U5A2-13, a mAb originally established for mouse NKT cells, recognizes a novel conformational epitope of ICAM-1."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.imlet.2004.01.005"xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Kato K."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Yoshida M."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Shimizu A."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Sasaki H."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Nagai H."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Shirakawa K."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Aoyagi K."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Miyajima A."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Wakasugi H."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Terada M."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Ikarashi Y."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Heike Y."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/author | "Takaue Y."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/name | "Immunol Lett"xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/pages | "227-235"xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/title | "The mouse natural killer T cell-associated antigen recognized by U5A2-13 monoclonal antibody is intercellular adhesion molecule-1."xsd:string |
http://purl.uniprot.org/citations/15081617 | http://purl.uniprot.org/core/volume | "92"xsd:string |
http://purl.uniprot.org/citations/15081617 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15081617 |
http://purl.uniprot.org/citations/15081617 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15081617 |
http://purl.uniprot.org/uniprot/#_P13597-mappedCitation-15081617 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15081617 |
http://purl.uniprot.org/uniprot/#_Q3THH5-mappedCitation-15081617 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15081617 |