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http://purl.uniprot.org/citations/15081617http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15081617http://www.w3.org/2000/01/rdf-schema#comment"Natural Killer T (NKT) cells in mice are generally defined as NK1.1(+) T cells, although NK1.1 antigen is expressed only in C57BL/6 and related strains. This has precluded investigations of other strains. To find a novel NKT cell surface marker, we generated a monoclonal antibody (mAb), U5A2-13, which recognizes phenotypically and functionally similar populations to NKT cells in naïve mice irrespective of strain. Here, by using a COS-7 expressional cloning system, we molecularly cloned a cDNA encoding a protein reactive with the U5A2-13 mAb and then identified it as intercellular adhesion molecule-1 (ICAM-1). Importantly, the U5A2-13 mAb did not stain hepatic mononuclear cells from ICAM-1 gene disrupted mice. Furthermore, Pepscan method disclosed that the discontinuous epitope for U5A2-13 mAb is composed of three loops located in extracellular domain two of ICAM-1. Overall, U5A2-13, a mAb originally established for mouse NKT cells, recognizes a novel conformational epitope of ICAM-1."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.org/dc/terms/identifier"doi:10.1016/j.imlet.2004.01.005"xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Kato K."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Yoshida M."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Shimizu A."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Sasaki H."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Nagai H."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Shirakawa K."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Aoyagi K."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Miyajima A."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Wakasugi H."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Terada M."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Ikarashi Y."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Heike Y."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/author"Takaue Y."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/name"Immunol Lett"xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/pages"227-235"xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/title"The mouse natural killer T cell-associated antigen recognized by U5A2-13 monoclonal antibody is intercellular adhesion molecule-1."xsd:string
http://purl.uniprot.org/citations/15081617http://purl.uniprot.org/core/volume"92"xsd:string
http://purl.uniprot.org/citations/15081617http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15081617
http://purl.uniprot.org/citations/15081617http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15081617
http://purl.uniprot.org/uniprot/#_P13597-mappedCitation-15081617http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15081617
http://purl.uniprot.org/uniprot/#_Q3THH5-mappedCitation-15081617http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15081617