http://purl.uniprot.org/citations/15094040 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15094040 | http://www.w3.org/2000/01/rdf-schema#comment | "The amounts of RNA polymerase I (Pol I) and basal rDNA transcription factors were determined in yeast whole cell extracts. A 17-fold excess of Pol I was found compared to the Pol I-specific initiation factors upstream activating factor (UAF) and core factor (CF) which underlines that both initiation factors interact with a minor fraction of Pol I when rDNA transcription is active. Surprisingly, Rrn3p, another Pol I-specific initiation factor, is more abundant in cell lysates than UAF and CF. Our analyses revealed that a large fraction of cellular Rrn3p is not associated with Pol I. However, the amount of initiation-active Rrn3p which forms a stable complex with Pol I corresponds to the levels of UAF and CF which have been shown to bind the promoter. Initiation-active Rrn3p dissociates from the template during or immediately after Pol I has switched from initiation to elongation. Our data support a model in which the elongating Pol I leaves the initiation factors UAF, CF and Rrn3p close by the promoter."xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(04)00311-4"xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/author | "Tschochner H."xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/author | "Fath S."xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/author | "Bier M."xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/pages | "41-46"xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/title | "The composition of the RNA polymerase I transcription machinery switches from initiation to elongation mode."xsd:string |
http://purl.uniprot.org/citations/15094040 | http://purl.uniprot.org/core/volume | "564"xsd:string |
http://purl.uniprot.org/citations/15094040 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15094040 |
http://purl.uniprot.org/citations/15094040 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15094040 |
http://purl.uniprot.org/uniprot/#_P53437-mappedCitation-15094040 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15094040 |
http://purl.uniprot.org/uniprot/#_P32786-mappedCitation-15094040 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15094040 |
http://purl.uniprot.org/uniprot/P32786 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15094040 |
http://purl.uniprot.org/uniprot/P53437 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15094040 |