| http://purl.uniprot.org/citations/15100437 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15100437 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15100437 | http://www.w3.org/2000/01/rdf-schema#comment | "The Saccharomyces cerevisiae gene RRP1 encodes an essential, evolutionarily conserved protein necessary for biogenesis of 60S ribosomal subunits. Processing of 27S pre-ribosomal RNA to mature 25S rRNA is blocked and 60S subunits are deficient in the temperature-sensitive rrp1-1 mutant. We have used recent advances in proteomic analysis to examine in more detail the function of Rrp1p in ribosome biogenesis. We show that Rrp1p is a nucleolar protein associated with several distinct 66S pre-ribosomal particles. These pre-ribosomes contain ribosomal proteins plus at least 28 nonribosomal proteins necessary for production of 60S ribosomal subunits. Inactivation of Rrp1p inhibits processing of 27SA(3) to 27SB(S) pre-rRNA and of 27SB pre-rRNA to 7S plus 25.5S pre-rRNA. Thus, in the rrp1-1 mutant, 66S pre-ribosomal particles accumulate that contain 27SA(3) and 27SB(L) pre-ribosomal RNAs."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.org/dc/terms/identifier | "doi:10.1261/rna.5255804"xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.org/dc/terms/identifier | "doi:10.1261/rna.5255804"xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Woolford J.L. Jr."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Woolford J.L. Jr."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Harnpicharnchai P."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Harnpicharnchai P."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Jakovljevic J."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Jakovljevic J."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Horsey E.W."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Horsey E.W."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Miles T.D."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/author | "Miles T.D."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/name | "RNA"xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/name | "RNA"xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/pages | "813-827"xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/pages | "813-827"xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/title | "Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/title | "Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation."xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/15100437 | http://purl.uniprot.org/core/volume | "10"xsd:string |