| http://purl.uniprot.org/citations/15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15105431 | http://www.w3.org/2000/01/rdf-schema#comment | "Protein-protein interactions are often mediated by small domains that recognize solvent-exposed peptide sequences. Deciphering the recognition code for these adapter domains is an important step in the understanding of multi-protein assemblies. Here, we investigate the sequence requirements for the CD2BP2-GYF domain, a proline-rich sequence binding module previously shown to be involved in T cell signaling. We show that the signature (R/K/G)XXPPGX(R/K) defines a preferred peptide-binding motif that is present in several proteins of the splicing machinery. Specifically, the core small nuclear ribonucleoprotein, SmB/B', contains several PPP-PGMR motifs that interact with the CD2BP2-GYF domain in vitro and in vivo. The colocalization of CD2BP2 and SmB proteins in the nucleus of Jurkat T cells and HeLa cells suggests a function of the GYF domain of CD2BP2 in mediating protein-protein interactions within the spliceosome."xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m402008200"xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/author | "Zech T."xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/author | "Freund C."xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/author | "Kofler M."xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/author | "Heuer K."xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/pages | "28292-28297"xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/title | "Recognition sequences for the GYF domain reveal a possible spliceosomal function of CD2BP2."xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://purl.uniprot.org/core/volume | "279"xsd:string |
| http://purl.uniprot.org/citations/15105431 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15105431 |
| http://purl.uniprot.org/citations/15105431 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15105431 |
| http://purl.uniprot.org/uniprot/#_A0A024QZC1-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_Q15637-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z5J7-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_P09012-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_Q15427-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_O95400-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_Q53HE7-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_P23246-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_P46934-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_O43426-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |
| http://purl.uniprot.org/uniprot/#_P06729-mappedCitation-15105431 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15105431 |