| http://purl.uniprot.org/citations/15105460 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15105460 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15105460 | http://www.w3.org/2000/01/rdf-schema#comment | "Parkin is an E3 ubiquitin ligase involved in the ubiquitination of proteins that are important in the survival of dopamine neurons in Parkinson's disease (PD). We show that parkin is S-nitrosylated in vitro, as well as in vivo in a mouse model of PD and in brains of patients with PD and diffuse Lewy body disease. Moreover, S-nitrosylation inhibits parkin's ubiquitin E3 ligase activity and its protective function. The inhibition of parkin's ubiquitin E3 ligase activity by S-nitrosylation could contribute to the degenerative process in these disorders by impairing the ubiquitination of parkin substrates."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1093891"xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1093891"xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Thomas B."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Thomas B."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Chung K.K.K."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Chung K.K.K."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Dawson T.M."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Dawson T.M."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Dawson V.L."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Dawson V.L."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Pletnikova O."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Pletnikova O."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Troncoso J.C."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Troncoso J.C."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Marsh L."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/author | "Marsh L."xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/15105460 | http://purl.uniprot.org/core/name | "Science"xsd:string |