| http://purl.uniprot.org/citations/15116308 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15116308 | http://www.w3.org/2000/01/rdf-schema#comment | "In 292 initially human immunodeficiency virus (HIV)-1-serodiscordant and cohabiting Zambian couples, HLA-DRB1 and -DQB1 variants were associated with HIV-1 transmission events during a 7-year follow-up period. Initially seronegative partners with either DRB1*0301-DQB1*0201 (relative hazard [RH], 1.60; P=.009) or DRB1*1503-DQB1*0602 (RH, 1.67; P=.03) showed accelerated seroconversion. Carriage of DRB1*1301 in initially seropositive partners led to delayed transmission of HIV to their spouses (RH, 0.54; P=.05). The combined groups of seroprevalent and seroincident partners (n=433) also differed from those who remained seronegative (n=151), with regard to 2 common haplotypes, DRB1*1302-DQB1*0604 (relative odds [RO], 0.28; P=.003) and DRB1*1503-DQB1*0602 (RO, 1.81; P=.02). Statistical adjustments for other host factors (age, sex, genital ulcer, and index partner's virus load) known to influence transmission of HIV-1 seldom altered the genetic relationships. Overall, associations of HLA class II polymorphisms with both HIV transmission and acquisition are not as readily interpretable as are effects reported for other loci."xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.org/dc/terms/identifier | "doi:10.1086/383280"xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/author | "Allen S."xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/author | "Kaslow R.A."xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/author | "Penman-Aguilar A."xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/author | "Lobashevsky E."xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/name | "J Infect Dis"xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/pages | "1696-1704"xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/title | "HLA-DRB1 and -DQB1 alleles and haplotypes in Zambian couples and their associations with heterosexual transmission of HIV type 1."xsd:string |
| http://purl.uniprot.org/citations/15116308 | http://purl.uniprot.org/core/volume | "189"xsd:string |
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