http://purl.uniprot.org/citations/15128042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15128042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15128042 | http://www.w3.org/2000/01/rdf-schema#comment | "Using a yeast two-hybrid screen, we identified Filamin-A as a binding partner of the new adapter protein c-mip (c-maf inducing protein) and it's splice variant Tc-mip (truncated c-maf inducing protein). We have previously shown that Tc-mip is involved in Th2 signaling pathway and cytoskeletal reorganization in patients with minimal change nephrotic syndrome (MCNS), the most frequent glomerular disease in children. We showed that Filamin-A and c-mip or Tc-mip co-immunoprecipitate from c-mip or Tc-mip Jurkat transfected cells using antibodies directed against both types of proteins. In co-immunoprecipitate Jurkat cells, Filamin-A and c-mip were distributed evenly in the cytoplasm, whereas in Tc-mip-transfected Jurkat cells, Filamin-A was expressed in zones facing the cell contact. Moreover, we found that Filamin-A was upregulated in T lymphocytes of MCNS patients, as compared to normal subjects. These findings suggest that Filamin-A interacts with c-mip/Tc-mip in this new T-cell signaling pathway."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2003.11.035"xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2003.11.035"xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Lang P."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Lang P."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Audard V."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Audard V."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Grimbert P."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Grimbert P."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Guellaen G."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Guellaen G."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Sahali D."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Sahali D."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Valanciute A."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/author | "Valanciute A."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/name | "Mol. Immunol."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/name | "Mol. Immunol."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/pages | "1257-1261"xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/pages | "1257-1261"xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/title | "The Filamin-A is a partner of Tc-mip, a new adapter protein involved in c-maf-dependent Th2 signaling pathway."xsd:string |
http://purl.uniprot.org/citations/15128042 | http://purl.uniprot.org/core/title | "The Filamin-A is a partner of Tc-mip, a new adapter protein involved in c-maf-dependent Th2 signaling pathway."xsd:string |