| http://purl.uniprot.org/citations/15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15133515 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcriptional control of the differentiation of central serotonergic (5-HT) neurons in vertebrates has recently come under scrutiny and has been shown to involve the homeobox genes Nkx2-2 and Lmx1b, the Ets-domain gene Pet1 (also known as Fev) and the zinc-finger gene Gata3. The basic helix-loop-helix (bHLH) gene Ascl1 (also known as Mash1) is coexpressed with Nkx2-2 in the neuroepithelial domain of the hindbrain, which gives rise to 5-HT neurons. Here we show in the mouse that Ascl1 is essential for the birth of 5-HT neurons, both as a proneural gene for the production of postmitotic neuronal precursors and as a determinant of the serotonergic phenotype for the parallel activation of Gata3, Lmx1b and Pet1. Thus Ascl1, which is essential for noradrenergic differentiation, is also a determinant of the serotonergic phenotype."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn1247"xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/author | "Guillemot F."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/author | "Goridis C."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/author | "Brunet J.F."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/author | "van Doorninck J.H."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/author | "Pattyn A."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/author | "Simplicio N."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/name | "Nat Neurosci"xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/pages | "589-595"xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/title | "Ascl1/Mash1 is required for the development of central serotonergic neurons."xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/15133515 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15133515 |
| http://purl.uniprot.org/citations/15133515 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15133515 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J0I7-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_A0A0N4SWF9-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_A0A1D5RM76-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_E0CXR7-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_P63015-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_A0A338P7A6-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_A2A409-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_A2A412-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |
| http://purl.uniprot.org/uniprot/#_A0A6I8MWW7-mappedCitation-15133515 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15133515 |