| http://purl.uniprot.org/citations/15136729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15136729 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15136729 | http://www.w3.org/2000/01/rdf-schema#comment | "The CD3 epsilon gamma heterodimer is essential for expression and function of the T cell receptor. The crystal structure of the human CD3 epsilon gamma heterodimer is described to 2.1-A resolution complexed with OKT3, a therapeutic mAb that not only activates and tolerizes mature T cells but also induces regulatory T cells. The mode of CD3 epsilon gamma dimerization provides a general structural basis for CD3 assembly and maps candidate T cell antigen receptor docking sites, including a duplicated linear region rich in acidic residues that is unique to human CD3 epsilon. OKT3 binds to an atypically small area of CD3 epsilon and has a low affinity for the isolated CD3 epsilon gamma heterodimer. The structure of the OKT3/CD3 epsilon gamma complex has implications for T cell signaling and therapeutic design."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0402295101"xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0402295101"xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Purcell A.W."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Purcell A.W."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Dunstone M.A."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Dunstone M.A."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Rossjohn J."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Rossjohn J."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Beddoe T."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Beddoe T."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Brooks A.G."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Brooks A.G."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Ely L.K."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Ely L.K."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Kjer-Nielsen L."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Kjer-Nielsen L."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "McCluskey J."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "McCluskey J."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Kostenko L."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Kostenko L."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Mifsud N.A."xsd:string |
| http://purl.uniprot.org/citations/15136729 | http://purl.uniprot.org/core/author | "Mifsud N.A."xsd:string |