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| http://purl.uniprot.org/citations/15150696 | http://www.w3.org/2000/01/rdf-schema#comment | "Peptidylarginine deiminases (PADIs) are post-translational modification enzymes that catalyze the conversion of protein-bound arginine residues into citrulline residues in the presence of calcium ions. Among PADIs, PADI4 was identified as a rheumatoid arthritis-susceptibility gene (Suzuki et al. in Nat Genet 34:395, 2003). We identified a total of 87 single nucleotide polymorphisms (SNPs) in PADI1 and PADI3 gene loci. Following a comparison of our data with SNPs in the dbSNP database in the National Center for Biotechnology Information, 45 SNPs are considered to be novel: 33 were identified in the PADI1 gene locus and 12 in the PADI3 gene locus. We also identified two insertion-deletion polymorphisms in introns of the PADI1. The high-resolution map that we constructed in this study will serve as a useful resource for analyzing gene scans of complex diseases mapped to this local segment on chromosomal band 1p36.13."xsd:string |
| http://purl.uniprot.org/citations/15150696 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10038-004-0156-1"xsd:string |
| http://purl.uniprot.org/citations/15150696 | http://purl.uniprot.org/core/author | "Nakamura Y."xsd:string |
| http://purl.uniprot.org/citations/15150696 | http://purl.uniprot.org/core/author | "Iida A."xsd:string |
| http://purl.uniprot.org/citations/15150696 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15150696 | http://purl.uniprot.org/core/name | "J Hum Genet"xsd:string |
| http://purl.uniprot.org/citations/15150696 | http://purl.uniprot.org/core/pages | "387-390"xsd:string |
| http://purl.uniprot.org/citations/15150696 | http://purl.uniprot.org/core/title | "Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13."xsd:string |
| http://purl.uniprot.org/citations/15150696 | http://purl.uniprot.org/core/volume | "49"xsd:string |
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