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http://purl.uniprot.org/citations/15164053http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15164053http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15164053http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15164053http://www.w3.org/2000/01/rdf-schema#comment"Chromosome 9 is highly structurally polymorphic. It contains the largest autosomal block of heterochromatin, which is heteromorphic in 6-8% of humans, whereas pericentric inversions occur in more than 1% of the population. The finished euchromatic sequence of chromosome 9 comprises 109,044,351 base pairs and represents >99.6% of the region. Analysis of the sequence reveals many intra- and interchromosomal duplications, including segmental duplications adjacent to both the centromere and the large heterochromatic block. We have annotated 1,149 genes, including genes implicated in male-to-female sex reversal, cancer and neurodegenerative disease, and 426 pseudogenes. The chromosome contains the largest interferon gene cluster in the human genome. There is also a region of exceptionally high gene and G + C content including genes paralogous to those in the major histocompatibility complex. We have also detected recently duplicated genes that exhibit different rates of sequence divergence, presumably reflecting natural selection."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.org/dc/terms/identifier"doi:10.1038/nature02465"xsd:string
http://purl.uniprot.org/citations/15164053http://purl.org/dc/terms/identifier"doi:10.1038/nature02465"xsd:string
http://purl.uniprot.org/citations/15164053http://purl.org/dc/terms/identifier"doi:10.1038/nature02465"xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ainscough R."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ainscough R."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ainscough R."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Almeida J.P."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Almeida J.P."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Almeida J.P."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ambrose K.D."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ambrose K.D."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ambrose K.D."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Andrews T.D."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Andrews T.D."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Andrews T.D."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ashurst J.L."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ashurst J.L."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ashurst J.L."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ashwell R.I.S."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ashwell R.I.S."xsd:string
http://purl.uniprot.org/citations/15164053http://purl.uniprot.org/core/author"Ashwell R.I.S."xsd:string