http://purl.uniprot.org/citations/15174222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15174222 | http://www.w3.org/2000/01/rdf-schema#comment | "The pathogenesis of Sjögren's syndrome (SS) is poorly understood. In this study we used an in-house mouse spleen cDNA microarray to analyse genes in spleens from MRL/lpr (an SS mouse model) mice. We have previously demonstrated that GRAP genes were up-regulated in salivary glands of the same mice. The microarray analysis showed that seven out of 2304 genes were highly expressed in spleens from the MRL/lpr mice, one of which was the GRAP gene. In other words, the GRAP gene is highly expressed in the salivary glands and spleen of MRL/lpr mice. We also carried out immunohistochemical studies. Mouse and human Grb-2-related adaptor protein (GRAP) antigens were expressed on ductal cells and infiltrating lymphocytes in salivary glands of MRL/lpr mice and SS patients, but only weakly in controls (MRL/+ mice and individuals with salivary cysts). These results suggest that the GRAP gene might have a role in the pathogenesis of SS."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.org/dc/terms/identifier | "doi:10.1177/147323000403200308"xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Kato M."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Sawada S."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Seki N."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Yoshikawa T."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Ueki T."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Horie T."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Azuma T."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Takei M."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Mitamura K."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Shiraiwa H."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/author | "Kida A."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/name | "J Int Med Res"xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/pages | "284-291"xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/title | "Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjogren's syndrome."xsd:string |
http://purl.uniprot.org/citations/15174222 | http://purl.uniprot.org/core/volume | "32"xsd:string |
http://purl.uniprot.org/citations/15174222 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15174222 |
http://purl.uniprot.org/citations/15174222 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15174222 |
http://purl.uniprot.org/uniprot/#_Q13588-mappedCitation-15174222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15174222 |
http://purl.uniprot.org/uniprot/#_I3L2P9-mappedCitation-15174222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15174222 |
http://purl.uniprot.org/uniprot/I3L2P9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15174222 |
http://purl.uniprot.org/uniprot/Q13588 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15174222 |