http://purl.uniprot.org/citations/15175327 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15175327 | http://www.w3.org/2000/01/rdf-schema#comment | "The SUMO family in vertebrates includes at least three distinct proteins (SUMO-1, -2, and -3) that are added as post-translational modifications to target proteins. A considerable number of SUMO-1 target proteins have been identified, but little is known about SUMO-2. A stable HeLa cell line expressing His6-tagged SUMO-2 was established and used to label and purify novel endogenous SUMO-2 target proteins. Tagged forms of SUMO-2 were functional and localized predominantly in the nucleus. His6-tagged SUMO-2 conjugates were affinity-purified from nuclear fractions and identified by mass spectrometry. Eight novel potential SUMO-2 target proteins were identified by at least two peptides. Three of these proteins, SART1, heterogeneous nuclear ribonucleoprotein (RNP) M, and the U5 small nuclear RNP 200-kDa helicase, play a role in RNA metabolism. SART1 and heterogeneous nuclear RNP M were both shown to be genuine SUMO targets, confirming the validity of the approach."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m404201200"xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Andersen J.S."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Hay R.T."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Mann M."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Vertegaal A.C."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Lamond A.I."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Rodriguez M.S."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Ogg S.C."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/author | "Jaffray E."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/pages | "33791-33798"xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/title | "A proteomic study of SUMO-2 target proteins."xsd:string |
http://purl.uniprot.org/citations/15175327 | http://purl.uniprot.org/core/volume | "279"xsd:string |
http://purl.uniprot.org/citations/15175327 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15175327 |
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