http://purl.uniprot.org/citations/15196926 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15196926 | http://www.w3.org/2000/01/rdf-schema#comment | "In ElasCCK2 transgenic mice expressing cholecystokinin (CCK2) receptor in acinar cells, pancreatic phenotypic alterations and preneoplastic lesions are observed. We determined whether activation of phospholipase C gamma1 (PLCgamma1), known to contribute to the tumorigenesis pathophysiology, could take place as a new signaling pathway induced by the CCK2 receptor. Overexpression and activation of the PLCgamma1 in response to gastrin was observed in acinar cells. The possibility that the C-terminal tyrosine 438 of the CCK2 receptor associates with the SH2 domains of PLCgamma1 was examined. A specific interaction was demonstrated using surface plasmon resonance, confirmed in a cellular system and by molecular modeling."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2004.05.012"xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Moroder L."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Fourmy D."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Dufresne M."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Ferrand A."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Tassa A."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Esteve J.P."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Archer E."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Arnould M."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Seva C."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Escherich A."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Penalba V."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/author | "Portolan G."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/pages | "89-93"xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/title | "The G-protein-coupled CCK2 receptor associates with phospholipase Cgamma1."xsd:string |
http://purl.uniprot.org/citations/15196926 | http://purl.uniprot.org/core/volume | "568"xsd:string |
http://purl.uniprot.org/citations/15196926 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15196926 |
http://purl.uniprot.org/citations/15196926 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15196926 |
http://purl.uniprot.org/uniprot/#_P56481-mappedCitation-15196926 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15196926 |
http://purl.uniprot.org/uniprot/#_A2A4A6-mappedCitation-15196926 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15196926 |
http://purl.uniprot.org/uniprot/#_G3UXP4-mappedCitation-15196926 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15196926 |