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http://purl.uniprot.org/citations/15196926http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15196926http://www.w3.org/2000/01/rdf-schema#comment"In ElasCCK2 transgenic mice expressing cholecystokinin (CCK2) receptor in acinar cells, pancreatic phenotypic alterations and preneoplastic lesions are observed. We determined whether activation of phospholipase C gamma1 (PLCgamma1), known to contribute to the tumorigenesis pathophysiology, could take place as a new signaling pathway induced by the CCK2 receptor. Overexpression and activation of the PLCgamma1 in response to gastrin was observed in acinar cells. The possibility that the C-terminal tyrosine 438 of the CCK2 receptor associates with the SH2 domains of PLCgamma1 was examined. A specific interaction was demonstrated using surface plasmon resonance, confirmed in a cellular system and by molecular modeling."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2004.05.012"xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Moroder L."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Fourmy D."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Dufresne M."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Ferrand A."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Tassa A."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Esteve J.P."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Archer E."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Arnould M."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Seva C."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Escherich A."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Penalba V."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/author"Portolan G."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/pages"89-93"xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/title"The G-protein-coupled CCK2 receptor associates with phospholipase Cgamma1."xsd:string
http://purl.uniprot.org/citations/15196926http://purl.uniprot.org/core/volume"568"xsd:string
http://purl.uniprot.org/citations/15196926http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15196926
http://purl.uniprot.org/citations/15196926http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15196926
http://purl.uniprot.org/uniprot/#_P56481-mappedCitation-15196926http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15196926
http://purl.uniprot.org/uniprot/#_A2A4A6-mappedCitation-15196926http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15196926
http://purl.uniprot.org/uniprot/#_G3UXP4-mappedCitation-15196926http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15196926