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http://purl.uniprot.org/citations/15203151http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15203151http://www.w3.org/2000/01/rdf-schema#comment"Through structure-based drug design and parallel synthesis, we have discovered a novel series of nonpeptidic phenyl-based thrombin inhibitors using oxyguanidines as guanidine bioisosteres. These compounds have been found to be highly potent, highly selective, and orally bioavailable."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2004.05.002"xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Lu T."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Giardino E.C."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Crysler C."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Spurlino J."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Bone R."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Soll R.M."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Coppo F."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Eisennagel S."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Gremminger L."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Markotan T."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/author"Tomczuk B."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/name"Bioorg Med Chem Lett"xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/pages"3727-3731"xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/title"Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis."xsd:string
http://purl.uniprot.org/citations/15203151http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/15203151http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15203151
http://purl.uniprot.org/citations/15203151http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/15203151
http://purl.uniprot.org/uniprot/#_P00734-mappedCitation-15203151http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15203151
http://purl.uniprot.org/uniprot/#_P28507-mappedCitation-15203151http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/15203151
http://purl.uniprot.org/uniprot/P00734http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15203151
http://purl.uniprot.org/uniprot/P28507http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/15203151