| http://purl.uniprot.org/citations/15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15225646 | http://www.w3.org/2000/01/rdf-schema#comment | "Previously, it was shown that the recruitment of RET into lipid rafts by glial cell line-derived neurotrophic factor (GDNF)/GFRalpha1 is crucial for efficient signal transduction. Here, we show that the mouse GFRalpha4 is a functional, N-glycosylated, glycosylphosphatidylinositol (GPI)-anchored protein, which mediates persephin (PSPN)-induced phosphorylation of RET, but has an almost undetectable capacity to recruit RET into the 0.1% Triton X-100 insoluble membrane fraction. In spite of this, PSPN/mGFRalpha4 promotes neurite outgrowth in PC6-3 cells and survival of cerebellar granule neurons. As we show that also human PSPN/GFRalpha4 is unable to recruit RET into lipid rafts, we propose that the mammalian GFRalpha4 in this respect differs from GFRalpha1."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2004.06.007"xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/author | "Saarma M."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/author | "Yang J."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/author | "Runeberg-Roos P."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/author | "Lindahl M."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/author | "Lindholm P."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/author | "Coffey E."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/author | "Virtanen H."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/pages | "267-271"xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/title | "PSPN/GFRalpha4 has a significantly weaker capacity than GDNF/GFRalpha1 to recruit RET to rafts, but promotes neuronal survival and neurite outgrowth."xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://purl.uniprot.org/core/volume | "569"xsd:string |
| http://purl.uniprot.org/citations/15225646 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15225646 |
| http://purl.uniprot.org/citations/15225646 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15225646 |
| http://purl.uniprot.org/uniprot/#_F5CNE9-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |
| http://purl.uniprot.org/uniprot/#_A2AP45-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |
| http://purl.uniprot.org/uniprot/#_B4DGX8-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |
| http://purl.uniprot.org/uniprot/#_A5D8Z1-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |
| http://purl.uniprot.org/uniprot/#_F8TLS5-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |
| http://purl.uniprot.org/uniprot/#_F8TLW0-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |
| http://purl.uniprot.org/uniprot/#_M9Z0T2-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |
| http://purl.uniprot.org/uniprot/#_Q2M2Q9-mappedCitation-15225646 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15225646 |