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| http://purl.uniprot.org/citations/15232111 | http://www.w3.org/2000/01/rdf-schema#comment | "During axon guidance, the ventral guidance of the Caenorhabditis elegans anterior ventral microtubule axon is controlled by two cues, the UNC-6/netrin attractant recognized by the UNC-40/DCC receptor and the SLT-1/slit repellent recognized by the SAX-3/robo receptor. We show here that loss-of-function mutations in clr-1 enhance netrin-dependent attraction, suppressing ventral guidance defects in slt-1 mutants. clr-1 encodes a transmembrane receptor protein tyrosine phosphatase (RPTP) that functions in AVM to inhibit signaling through the DCC family receptor UNC-40 and its effector, UNC-34/enabled. The known effects of other RPTPs in axon guidance could result from modulation of guidance receptors like UNC-40/DCC."xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1096983"xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/author | "Chang C."xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/author | "Tessier-Lavigne M."xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/author | "Yu T.W."xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/author | "Bargmann C.I."xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/pages | "103-106"xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/title | "Inhibition of netrin-mediated axon attraction by a receptor protein tyrosine phosphatase."xsd:string |
| http://purl.uniprot.org/citations/15232111 | http://purl.uniprot.org/core/volume | "305"xsd:string |
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