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http://purl.uniprot.org/citations/15234001http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15234001http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15234001http://www.w3.org/2000/01/rdf-schema#comment"We performed high-throughput in situ hybridization screening of sections of mouse epidermis using an equalized skin cDNA library as probes and identified a novel gene giving rise to two splicing variants, both of which are expressed in the spinous layer. This gene was mapped between two genes encoding keratinocyte-related peptides, suprabasin and keratinocyte differentiation-associated protein (Kdap), on human chromosome 19q13.1. These gene products appeared to carry functional signal sequences. We then designated these two splicing variants as dermokine-alpha and -beta. Northern blotting and quantitative RT-PCR revealed that dermokine-alpha/-beta, suprabasin, and Kdap were highly expressed in stratified epithelia. In mouse embryonic development, dermokine-alpha/-beta began to be expressed during the period of stratification. Also, in differentiating primary cultured human keratinocytes, transcription of dermokine-alpha/-beta, suprabasin, and Kdap was induced. These findings indicated that dermokine-alpha/-beta, suprabasin, and Kdap are secreted from the spinous layer of the stratified epithelia and that these genes form a novel gene complex on the chromosome."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.org/dc/terms/identifier"doi:10.1016/j.ygeno.2004.03.010"xsd:string
http://purl.uniprot.org/citations/15234001http://purl.org/dc/terms/identifier"doi:10.1016/j.ygeno.2004.03.010"xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Komiya T."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Komiya T."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Imai T."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Imai T."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Ono Y."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Ono Y."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Tsukita S."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Tsukita S."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Matsui T."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Matsui T."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Morita K."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Morita K."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Hayashi-Kisumi F."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Hayashi-Kisumi F."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Miyachi Y."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Miyachi Y."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Tanigawa Y."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Tanigawa Y."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Kinoshita Y."xsd:string
http://purl.uniprot.org/citations/15234001http://purl.uniprot.org/core/author"Kinoshita Y."xsd:string