| http://purl.uniprot.org/citations/15237973 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15237973 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15237973 | http://www.w3.org/2000/01/rdf-schema#comment | "Among the numerous well-characterized families of glycosidases, family 4 appears to be the anomaly, requiring both catalytic NAD+ and a divalent metal for activity. The unusual cofactor requirement prompted the proposal of a mechanism involving key NAD+-mediated redox steps as well as elimination of the glycosidic oxygen. Primary kinetic isotope effects for the 2- and 3-deutero substrate analogues, isotopic exchange with solvent, and structural analysis of a 6-phospho-beta-glucosidase, BglT (E.C. 3.2.1.6), provided evidence in support of the proposed mechanism, which has striking resemblances to that of the sugar dehydratases. Furthermore, analysis of the stereochemical outcome indicated that family 4 enzymes are retaining glycosidases."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.org/dc/terms/identifier | "doi:10.1021/ja047632w"xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.org/dc/terms/identifier | "doi:10.1021/ja047632w"xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Anderson W.F."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Anderson W.F."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Davies G.J."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Davies G.J."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Rajan S.S."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Rajan S.S."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Thompson J."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Thompson J."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Yang X."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Yang X."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Varrot A."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Varrot A."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Withers S.G."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Withers S.G."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Yip V.L.Y."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/author | "Yip V.L.Y."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/name | "J. Am. Chem. Soc."xsd:string |
| http://purl.uniprot.org/citations/15237973 | http://purl.uniprot.org/core/name | "J. Am. Chem. Soc."xsd:string |