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http://purl.uniprot.org/citations/15240124http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15240124http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15240124http://www.w3.org/2000/01/rdf-schema#comment"Saccharomyces cerevisiae Ufd2 is a ubiquitin chain elongation factor in the ubiquitin fusion degradation (UFD) pathway and functions in stress tolerance. A recent study has suggested that the mammalian Ufd2 homologue UFD2a catalyzes formation of Lys27- and Lys33-linked polyubiquitin chains rather than the Lys48-linked chain, but the linkage type of the polyubiquitin chain formed by yeast Ufd2 remains unclear. To determine the property of Ufd2, we reconstituted the UFD pathway using purified enzymes from yeast. Direct determination of the ubiquitin chain linkage type in polyubiquitinated UFD substrates by MALDI-TOF mass spectrometry revealed that Ufd2 catalyzes elongation of the ubiquitin chain through Lys48 linkage."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2004.05.216"xsd:string
http://purl.uniprot.org/citations/15240124http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2004.05.216"xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Toh-e A."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Toh-e A."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Saeki Y."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Saeki Y."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Yokosawa H."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Yokosawa H."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Tayama Y."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/author"Tayama Y."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/pages"840-845"xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/pages"840-845"xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/title"Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/title"Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage."xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/volume"320"xsd:string
http://purl.uniprot.org/citations/15240124http://purl.uniprot.org/core/volume"320"xsd:string
http://purl.uniprot.org/citations/15240124http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15240124
http://purl.uniprot.org/citations/15240124http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/15240124