http://purl.uniprot.org/citations/15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/15254914 | http://www.w3.org/2000/01/rdf-schema#comment | "Presenilin 1 (PS1) is the gene responsible for the development of early-onset familial Alzheimer's disease. PS1-deficient mice have been reported to show defects in neurogenesis, somitogenesis and angiogenesis. Here, we report cardiac anomaly in PS1-deficient mice: the mutant hearts exhibited ventricular septal defect, double outlet right ventricle, and stenosis in the pulmonary artery. Immunohistochemistry using anti-PS1 antibody revealed the prominent expression of PS1 in mesenchymal cells at the septal area of the wild-type heart. These results suggest that PS1 may play an essential role in heart development."xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.org/dc/terms/identifier | "doi:10.1002/dvdy.20098"xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/author | "Nakajima M."xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/author | "Koseki H."xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/author | "Shirasawa T."xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/author | "Moriizumi E."xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/name | "Dev Dyn"xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/pages | "795-799"xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/title | "Presenilin 1 is essential for cardiac morphogenesis."xsd:string |
http://purl.uniprot.org/citations/15254914 | http://purl.uniprot.org/core/volume | "230"xsd:string |
http://purl.uniprot.org/citations/15254914 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15254914 |
http://purl.uniprot.org/citations/15254914 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15254914 |
http://purl.uniprot.org/uniprot/P49769#attribution-88312C4E5424A3FC3279983F9061C63D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/#_B1ARA9-mappedCitation-15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/#_B1ARB3-mappedCitation-15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/#_P49769-mappedCitation-15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/#_Q8CAW4-mappedCitation-15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/#_Q08481-mappedCitation-15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/#_Q3TDW2-mappedCitation-15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/#_Q3UYK2-mappedCitation-15254914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/Q08481 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/B1ARA9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15254914 |
http://purl.uniprot.org/uniprot/Q8CAW4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/15254914 |