| http://purl.uniprot.org/citations/15265023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15265023 | http://www.w3.org/2000/01/rdf-schema#comment | "We determined the occurrence of the single nucleotide polymorphisms (SNPs) -403A/G and -28C/G in the promoter region of RANTES in 1082 Chinese blood donors from northern and southern China and 249 HIV patients from southern China. Compared to healthy adults, Chinese AIDS patients had a significantly higher frequency of the -403G allele and haplotype I, -403G/-28C (P < 0.05), and a lower frequency of the -403A/A genotype (P < 0.01). Symptomatic patients had a higher frequency of the -28G allele and a lower frequency of the -28C/C genotype (P < or = 0.01). The plasma RANTES level was significantly lower in blood donors homozygous for haplotype I than in those who were homozygous for haplotypes II and III (P < 0.05). The frequency of the -403G allele was found to be higher in Chinese than in indigenous Africans, but lower than in Caucasians, Hispanics, and African Americans. The frequency of the -28G allele was comparable in Chinese and Japanese; this allele is rare in other ethnic groups. Results suggest that -403G may be associated with increased susceptibility to HIV infection, while -28G may be associated with advanced disease progression. The impact of SNPs on HIV infection appears to be unique in Chinese."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2370.2004.00466.x"xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Lee S.S."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Ng M.H."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Ma S."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Yuen K.Y."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Zhao X.Y."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Chan K.C."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Wong K.H."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Yam W.C."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/author | "Zheng B.J."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/name | "Eur J Immunogenet"xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/pages | "179-183"xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/title | "Effects of single nucleotide polymorphisms in the RANTES promoter region in healthy and HIV-infected indigenous Chinese."xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://purl.uniprot.org/core/volume | "31"xsd:string |
| http://purl.uniprot.org/citations/15265023 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15265023 |
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