http://purl.uniprot.org/citations/1527002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1527002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1527002 | http://www.w3.org/2000/01/rdf-schema#comment | "The complete primary structure of the general form of human beta-spectrin (beta G) has been deduced from cDNAs isolated from human brain. beta G-Spectrin is encoded by a gene located on human chromosome 2. beta G-Spectrin and erythrocyte beta-spectrin (beta R) share identical domain organization, with sequence identity of 60% and sequence similarity of 77%. beta-Spectrins have closely related N-terminal domains implicated in binding to actin, and 17 copies of a 106-residue repeat motif with consensus residues that are highly conserved between beta-spectrins as well as alpha-spectrins. C-terminal domains of beta G and the 270-kDa beta R-spectrins are candidate regions to associate with alpha-spectrin, and exhibit 75% similarity. beta G- and beta R-spectrins exhibit different patterns of expression in tissues and follow different developmental programs in those tissues where they are co-expressed. beta G-Spectrin is present in all tissues examined except for erythrocytes, while beta R-spectrin could be detected only in erythrocytes, brain, and heart. beta G- and beta R-Spectrins are both expressed in brain, but beta R appeared later in post-natal development and was highly enriched in cerebellum in contrast to the broad regional distribution of beta G-spectrin. beta-Spectrins are likely to perform related but distinct functions, with beta G in a general, constitutive role and beta R-spectrin involved in more specialized activities of differentiated cells."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)37020-6"xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)37020-6"xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/author | "Bennett V."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/author | "Bennett V."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/author | "Hu R.J."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/author | "Hu R.J."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/pages | "18715-18722"xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/pages | "18715-18722"xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/title | "Characterization of human brain cDNA encoding the general isoform of beta-spectrin."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/title | "Characterization of human brain cDNA encoding the general isoform of beta-spectrin."xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/volume | "267"xsd:string |
http://purl.uniprot.org/citations/1527002 | http://purl.uniprot.org/core/volume | "267"xsd:string |
http://purl.uniprot.org/citations/1527002 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1527002 |
http://purl.uniprot.org/citations/1527002 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1527002 |
http://purl.uniprot.org/citations/1527002 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1527002 |
http://purl.uniprot.org/citations/1527002 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1527002 |