| http://purl.uniprot.org/citations/1527016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1527016 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1527016 | http://www.w3.org/2000/01/rdf-schema#comment | "The Saccharomyces cerevisiae YDJ1 protein (YDJ1p) contains a C-terminal "CaaX box" motif common to proteins that are modified by prenylation. In the present study we show that YDJ1p is a specific substrate for both yeast and mammalian protein farnesyltransferase enzymes in vitro. A mutant form of YDJ1p, in which the conserved cysteine of the CaaX box is mutated to a serine (ydj1-S406p), cannot be farnesylated in vitro. After expression in S. cerevisiae, ydj1-S406p displays a reduced electrophoretic mobility and an increased cytosolic localization in subcellular fractionation experiments when compared to wild type YDJ1p. Expression of ydj1-S406 in cells lacking YDJ1 results in a temperature-sensitive growth phenotype in S. cerevisiae. These data indicate that farnesylation of YDJ1p is required for its function at elevated temperatures."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)37044-9"xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)37044-9"xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Tsai J."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Tsai J."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Casey P.J."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Casey P.J."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Douglas M.G."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Douglas M.G."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Caplan A.J."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/author | "Caplan A.J."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/pages | "18890-18895"xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/pages | "18890-18895"xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/title | "Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/title | "Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/volume | "267"xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://purl.uniprot.org/core/volume | "267"xsd:string |
| http://purl.uniprot.org/citations/1527016 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1527016 |
| http://purl.uniprot.org/citations/1527016 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1527016 |